When should one subtract background fluorescence in 2-color microarrays?
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چکیده
منابع مشابه
When should one subtract background fluorescence in 2-color microarrays?
Two-color microarrays are a powerful tool for genomic analysis, but have noise components that make inferences regarding gene expression inefficient and potentially misleading. Background fluorescence, whether attributable to nonspecific binding or other sources, is an important component of noise. The decision to subtract fluorescence surrounding spots of hybridization from spot fluorescence h...
متن کاملWhen should one subtract background fluorescence in two color microarrays?
Two color microarrays are a powerful tool for genomic analysis, but have noise components that make inferences regarding gene expression inefficient and potentially misleading. Background fluorescence, whether attributable to non-specific binding or other sources, is an important component of noise. The decision to subtract fluorescence surrounding spots of hybridization from spot fluorescence ...
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ژورنال
عنوان ژورنال: Biostatistics
سال: 2006
ISSN: 1465-4644,1468-4357
DOI: 10.1093/biostatistics/kxl041